The cannabinoids, including cannabinoid acids, are chiral compounds. The vast majority of naturally occurring products are chiral too. A chiral molecule is one that cannot be superimposed on its own mirror image. That means it has unique asymmetry which means it has a unique shape. That shape is important because in nature, even if a molecule has the right ‘chemistry’, if it is the wrong shape, it won’t work because it cannot fit into the site to react.
We also describe this characteristic as handedness; our hands are chiral and so are we. This may seem somewhat trivial but at the molecular level it is the difference between life and not life. Nature is not ambidextrous.
So lets get to the meat of the matter. The three main cannabinoids found in the cannabis plant are:
CBG-a (-)trans-d9-cannabigerolic acid,
CBD-a (-)trans-cannabidiolic acid, and
THC- a (-)trans-d9-tetrahydrocannabinolic acid.
The implications of this are far reaching because:
- If we process natural products we need to be aware of
that allows the molecules to have very unique and specific functions.
Processing chiral compounds.
Maintaining the chirality.